The Eleventh Revision of the World Health Organization’s International Classification of Diseases (ICD-11) was approved by the Seventy-second World Health Assembly, comprising the health ministers of all World Health Organization (WHO) Member States, on 25 May 2019. ICD-11 represents the first major, comprehensive revision of the ICD in nearly 30 years, and incorporates major advances in scientific evidence, best clinical practices and health information systems. The development and maintenance of international classification systems for health and the standardization of diagnostic procedures are core constitutional functions of WHO. By international treaty, WHO’s 194 Member States agree to use the ICD as the standard for the reporting of health information to WHO. The ICD is therefore the fundamental global framework for monitoring mortality and morbidity, epidemics and other threats to public health, and disease burden. Reporting of health statistics to WHO based on the new system began on 1 January 2022.

Disorders due to substance use or addictive behaviours p.441

Disorders due to substance use p.441
6C40 Disorders due to use of alcohol

Substance classes p.442
6C41 Disorders due to use of cannabis
6C42 Disorders due to use of synthetic cannabinoids
6C43 Disorders due to use of opioids
6C44 Disorders due to use of sedatives, hypnotics or anxiolytics
6C45 Disorders due to use of cocaine
6C46 Disorders due to use of stimulants, including amfetamines, methamfetamine and methcathinone
6C47 Disorders due to use of synthetic cathinones
6C48 Disorders due to use of caffeine
6C49 Disorders due to use of hallucinogens
6C4A Disorders due to use of nicotine
6C4B Disorders due to use of volatile inhalants
6C4C Disorders due to use of mdma or related drugs, including mda
6C4D Disorders due to use of dissociative drugs, including ketamine and phencyclidine (PCP)
6C4E Disorders due to use of other specified psychoactive substances, including medications
6C4F Disorders due to use of multiple specified psychoactive substances, including medications
6C4G Disorders due to use of unknown or unspecified psychoactive substances
6C4H Disorders due to use of non-psychoactive substances
6C4Z Disorders due to substance use, unspecified

Diagnostic requirements for disorders due to substance use p.455
Episode of harmful psychoactive substance use
Harmful pattern of psychoactive substance use
Substance dependence
Substance intoxication
Substance withdrawal

Substance-induced mental disorders p.488
Substance-induced delirium
Substance-induced psychotic disorders
Substance-induced mood disorders
Substance-induced anxiety disorders
Substance-induced obsessive-compulsive and related disorders
Substance-induced impulse control disorders
Substance-induced mental disorders listed in other groupings
Other specified disorder due to psychoactive substance use
Disorders due to psychoactive substance use, unspecified
6C4H  Disorders due to use of non-psychoactive substances
6C4Z Disorders due to substance use, unspecified

Hazardous substance use p.505
QE10 Hazardous alcohol use
QE11 Hazardous drug use
QE12 Hazardous nicotine use

Disorders due to addictive behaviours p.506
6C50 Gambling disorder
6C51 Gaming disorder
6C5Y Other specified disorder due to addictive behaviours
6C5Z Disorder due to addictive behaviours, unspecified

Hazardous gambling or betting and hazardous gaming p.516
QE21 Hazardous gambling or betting
QE22 Hazardous gaming Impulse control disorders