Alcohol, smoking and drug related indicators continue to show some of the largest health inequalities monitored in NI. Inequality gaps for drug related mortality and deaths due to drug misuse widened over the period analysed, with drug related mortality in the most deprived areas five times the rate seen in the least deprived. The alcohol specific mortality gap remained very large with the rate in the most deprived areas almost five times the rate in the least deprived. Despite a rise In alcohol related admission rates across all areas, and a narrowing in the resultant inequality gap, the rate in the most deprived areas was more than four and a half times that seen in the least deprived.