This article aimed to fill a perceived gap in the analysis of Irish social policy, by reviewing social policy relating to drug problems and alleviation policies over the previous 25 years. The period was divided into three phases: 1966-70 - The early years; 1980-85 - The opiate epidemic; 1986-91 - The AIDS connection. Within these periods, changes in policy and legislation were presented chronologically. In his discussion, the author examined the following questions: How clearly have drug problems been defined and which institutions have been given responsibility for their control? What have been the major external influences on Irish drug policy? Have causal relationships been sought/accepted between drug problems and other social problems? What policy-making structures have evolved in Ireland over the years?