Home > Medicines associated with dependence or withdrawal symptoms: safe prescribing and withdrawal management for adults.

National Institute for Health and Care Excellence. (2022) Medicines associated with dependence or withdrawal symptoms: safe prescribing and withdrawal management for adults. London: National Institute for Health and Care Excellence. NICE guideline [NG215].

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External website: https://www.nice.org.uk/guidance/NG215

This guideline covers general principles for prescribing and managing withdrawal from opioids, benzodiazepines, gabapentinoids, Z‑drugs and antidepressants in primary and secondary care.

This guideline includes recommendations on:

 

  • supporting people taking a dependence-forming medicine or antidepressant
  • making decisions about prescribing and taking a medicine
  • starting a medicine, including information and support, management planning, prescribing strategies and working with other healthcare professionals
  • reviewing a medicine
  • making shared decisions about withdrawing medicines
  • dose reduction, managing withdrawal symptoms and interventions to support withdrawal

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