Jonovska, Suzana and Sugnet, Tom and Šendula-Jengić, Vesna (2021) High-dose methylphenidate use prior to hospitalization exacerbates the withdrawal syndrome in inpatients treated for opioid and sedative-hypnotic co-dependence - case series and review of the literature. Psychiatria Danubina, 33, (Suppl 4), pp. 1240-1242.
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Methylphenidate (MPD) is a psychostimulant with dopamine and noradrenaline reuptake inhibition characteristics, frequently prescribed for treatment of narcolepsy and attention deficit hyperactivity disorder (ADHD). Synthesized in 1944, and subsequently marketed in 1954, it was initially used for treatment of hypotension, narcolepsy and sedative-induced coma. From the 1960ies, it has been prescribed for the treatment of ADHD, and this is most common indication of the drug, even not without controversy. Presently, it is among the fifty most prescribed medications in the USA, but less so in other countries. Similar to other stimulant psychotropic drugs, the abuse of MPD is common, especially among students, long-distance drivers and in people with substance use disorder....
B Substances > CNS stimulants
B Substances > Opioids (opiates)
G Health and disease > Substance use disorder > Multiple substance use (Poly-drug /Poly-substance)
G Health and disease > Substance use disorder > Drug use disorder > Drug withdrawal
J Health care, prevention, harm reduction and treatment > Patient / client care management
VA Geographic area > International
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