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Article

Huddleston, William Ryan and Robert Lyness, James and Quinn, Amy (2024) Review of the demographic factors and toxicology related to deaths due to pregabalin in Northern Ireland. Journal of Forensic and Legal Medicine , 101 .

Durand, Louise and O'Kane, Aoife and Tierney, Julie and Cronly, Mark and Bennett, Kathleen E and Kavanagh, Yvonne and Keenan, Eamon and Cousins, Gráinne (2023) Gabapentinoids in Ireland 2010 to 2020: an observational study of trends in gabapentinoid prescribing, law enforcement drug seizures and post mortem toxicology. British Journal of Clinical Pharmacology , Early online .

Durand, Louise and Keenan, Eamon and O'Reilly, Deirdre and Bennett, Kathleen and O'Hara, Andy and Cousins, Gráinne (2023) Prescription drugs with potential for misuse in Irish prisons: analysis of national prison prescribing trends, by gender and history of opioid use disorder, 2012 to 2020. BMC Psychiatry , 23 .

Cousins, Gráinne and Durand, Louise and O'Kane, Aoife and Tierney, Julie and Maguire, Richard and Stokes, Siobhán and O'Reilly, Deirdre and Arensman, Ella and Bennett, Kathleen E and Vázquez, María Otero and Corcoran, Paul and Lyons, Suzi and Kavanagh, Yvonne and Keenan, Eamon (2023) Prescription drugs with potential for misuse: protocol for a multi-indicator analysis of supply, detection and the associated health burden in Ireland between 2010 and 2020. BMJ Open , 13 , (3) .

Nahar, Limon K and Paterson, Sue (2023) Reclassification of pregabalin in the UK: has it made a difference in deaths? Journal of Analytical Toxicology , 47 , (1) .

Walde, Jonatan and Andersson, Lisa and Johnson, Björn and Håkansson, Anders (2023) Drug prescriptions preceding opioid-related deaths-a register study in forensic autopsy patients. PLoS ONE , 18 , (5) .

Domzaridou, Eleni and Carr, Matthew J and Millar, Tim and Webb, Roger T and Ashcroft, Darren M (2023) Non-fatal overdose risk associated with prescribing opioid agonists concurrently with other medication: Cohort study conducted using linked primary care, secondary care and mortality records. Addiction , 118 , (12) , pp. 2374-2383.

Soeiro, Thomas and Pradel, Vincent and Lapeyre-Mestre, Maryse and Micallef, Joëlle (2023) Systematic assessment of non-medical use of prescription drugs using doctor-shopping indicators: a nationwide, repeated cross-sectional study. Addiction , 118 , (10) , pp. 1984-1993.

Gittins, Rosalind and Vaziri, Roya and Maidment, Ian (2022) Surveying over the counter and prescription only medication misuse in treatment services during COVID-19. Substance Abuse: Research and Treatment , 16 .

Shyu, Claire and Chavez, Sofia and Boileau, Isabelle and Foll, Bernard Le (2022) Quantifying GABA in addiction: a review of proton magnetic resonance spectroscopy studies. Brain Sciences , 12 , (7) .

Lynn, Ena and Cousins, Gráinne and Lyons, Suzi and Bennett, Kathleen E (2022) Comparing characteristics of suicide to non-suicide drug poisoning deaths, by sex, in Ireland. Journal of Affective Disorders , 306 , pp. 80-89.

Tardelli, Vitor S and Bianco, Martina CM and Prakash, Rashmik and Segura, Luis C and Castaldelli-Maia, João M and Fidalgo, Thiago M and Martins, Silvia S (2022) Overdose deaths involving non-BZD hypnotic/sedatives in the USA: trends analyses. The Lancet Regional Health - Americas , 10 , p. 100190. (In Press)

Murnion, Bridin and Schaffer, Andrea and Cairns, Rose and Brett, Jonathan (2022) Gabapentinoids: repeating mistakes of the past? Addiction , 117 , (12) , pp. 2969-2971.

Whitfield, Mark and Germain, Jennifer and Hillis, Alice and Halsall, Devina and McVeigh, James and Abbasi, Yasir and Van Hout, Marie Claire (2021) Internet sourcing and UK end consumer trend interest in the controlled medicines (opioids, sedatives and GABA drugs) in pre and post COVID-19 timeframes. Emerging Trends in Drugs, Addictions, and Health , 1 , (100027) .

Rahman, Alvi and Kane, Joseph and Montastruc, François and Renoux, Christel (2021) Trends in new prescription of gabapentinoids and of coprescription with opioids in the 4 nations of the UK, 1993-2017. British Journal of Clinical Pharmacology , 87 , (8) , pp. 3349-3353.

Thiemt, Britta (2020) Qualitative insights into pregabalin use among individuals in opioid agonist treatment. Drugnet Ireland , Issue 74, Summer 2020 , pp. 12-14.

Rentsch, Christopher T and Morford, Kenneth L and Fiellin, David A and Bryant, Kendall J and Justice, Amy C and Tate, Janet P (2020) Safety of gabapentin prescribed for any indication in a large clinical cohort of 571,718 US Veterans with and without alcohol use disorder. Alcoholism, Clinical and Experimental Research , 44 , (9) , pp. 1807-1815.

Lyons, Suzi (2020) Appropriate prescribing of pregabalin. Drugnet Ireland , Issue 73, Spring 2020 , pp. 21-22.

Vold, Jørn Henrik and Skurtveit, Svetlana and Aas, Christer and Chalabianloo, Fatemeh and Kloster, Pia Synnøve and Johansson, Kjell Arne and Fadnes, Lars Thore (2020) Dispensations of benzodiazepines, z-hypnotics, and gabapentinoids to patients receiving opioid agonist therapy; a prospective cohort study in Norway from 2013 to 2017. BMC Health Services Research , 20 , (352) , p. 352.

Lynn, Ena (2020) Repeated cross-sectional study of factors associated with pregabalin-positive poisoning deaths in Ireland. Drugnet Ireland , Issue 72, Winter 2020 , pp. 16-17.

Brennan, Rebekah and Van Hout, Marie Claire (2020) "Bursting the Lyrica bubble”: experiences of pregabalin use in individuals accessing opioid agonist treatment in Dublin, Ireland. Heroin Addiction and Related Clinical Problems , 22 , (6) , pp. 5-13.

Lynn, Ena and Cousins, Gráinne and Lyons, Suzi and Bennett, Kathleen E (2020) A repeated cross-sectional study of factors associated with pregabalin-positive poisoning deaths in Ireland. Drug and Alcohol Dependence , 206 , (107741) .

Bonnet, Udo and Specka, Michael and Soyka, Michael and Alberti, Thomas and Bender, Stefan and Grigoleit, Torsten and Hermle, Leopold and Hilger, Jörg and Hillemacher, Thomas and Kuhlmann, Thomas and Kuhn, Jens and Luckhaus, Christian and Lüdecke, Christel and Reimer, Jens and Schneider, Udo and Schroeder, Welf and Stuppe, Markus and Wiesbeck, Gerhard A and Wodarz, Norbert and McAnally, Heath and Scherbaum, Norbert (2020) Ranking the harm of psychoactive drugs including prescription analgesics to users and others-a perspective of German addiction medicine experts. Frontiers in Psychiatry , 11 , p. 592199.

Lynn, Ena (2019) Has an increase in the dispensing of pregabalin influenced poisoning deaths in Ireland? Drugnet Ireland , Issue 71, Autumn 2019 , pp. 15-17.

MacCleod, John and Steer, Colin and Tilling, Kate and Cornish, Rosie and Marsden, John and Millar, Tim and Strang, John and Hickman, Matthew (2019) Prescription of benzodiazepines, z-drugs, and gabapentinoids and mortality risk in people receiving opioid agonist treatment: observational study based on the UK Clinical Practice Research Datalink and Office for National Statistics death records. PLoS ONE , 16 , (11) , e1002965.

Green, Katlyn and Cooke O'Dowd, Nora and Watt, Hilary and Majeed, Azeem and Pinder, Richard J (2019) Prescribing trends of gabapentin, pregabalin, and oxycodone: a secondary analysis of primary care prescribing patterns in England. BJGP Open , 3 , (3) .

Kranzler, Henry R and Feinn, Richard and Morris, Paige and Hartwell, Emily E (2019) A meta-analysis of the efficacy of gabapentin for treating alcohol use disorder. Addiction , 114 , (9) , pp. 1547-1555.

Nielsen, Suzanne and Gowing, Linda and Sabioni, Pamela and Le Foll, Bernard (2019) Pharmacotherapies for cannabis dependence. Cochrane Database of Systematic Reviews , (1) .

Schifano, Fabrizio and Chiappini, Stephania (2019) Pregabalin: a range of misuse‐related unanswered questions. CNS Neuroscience & Therapeutics , 25 , (5) .

Millar, Sean (2019) Pregabalin and gabapentin reclassified as controlled drugs in the UK. Drugnet Ireland , Issue 68, Winter 2019 , p. 20.

Bonnet, Udo and Richter, Emily-Lisa and Isbruch, Katrin and Scherbaum, Norbert (2018) On the addictive power of gabapentinoids: a mini-review. Psychiatria Danubina , 30 , (2) , pp. 142-149.

Banndrup, Lone and Ebdrup, Bjorn J and Rasmussen, Jesper O and Lindschou, Jane and Gluud, Christian and Glenthoj, Birte J (2018) Pharmacological interventions for benzodiazepine discontinuation in chronic benzodiazepine users. Cochrane Database of Systematic Reviews .

Lynn, Ena and Lyons, Suzi (2018) Drug-related deaths and deaths among drug users 2004–2015. Drugnet Ireland , Issue 64, Winter 2018 , pp. 4-6.

Lyons, Suzi (2018) Overview on pregabalin and gabapentin. Drugnet Ireland , Issue 65, Spring 2018 , pp. 11-12.

Daly, Caroline and Griffin, Eve and Ashcroft, Darren M and Webb, Roger T and Perry, Ivan J and Arensman, Ella (2018) Intentional drug overdose involving pregabalin and gabapentin: findings from the National Self-Harm Registry Ireland, 2007-2015. Clinical Drug Investigation , 38 , (4) , pp. 373-380.

Lyndon, Abigail and Audrey, Suzanne and Wells, Claudia and Burnell, Erica S and Ingle, Suzanne and Hill, Rob and Hickman, Matthew and Henderson, Graeme (2017) Risk to heroin users of polydrug use of pregabalin or gabapentin. Addiction , 112 , (9) , pp. 1580-1589.

Corrigan, Desmond (2017) Concern increasing over the emergence of pregabalin as a drug of abuse. Irish Pharmacist , 3 , (18) , 20 p..

McGuire, Vivion (2016) Drug and alcohol trends in Blanchardstown. Drugnet ireland , Issue 58, Summer 2016 , p. 14.

McNamara, Sinead and Stokes, Siobhan and Kilduff, R and Shine, A (2015) Pregabalin abuse amongst opioid substitution treatment patients. Irish Medical Journal , 108 , (10) .

Minozzi, Silvia and Cinquini, Michela and Amato, Laura and Davoli, Marina and Farrell, Michael and Pani, Pier Paolo and Vecchi, Simona (2015) Anticonvulsants for cocaine dependence. Cochrane Database of Systematic Reviews , (4) .

Osman, M and Casey, P (2014) Pregabalin abuse for enhancing sexual performance: case discussion and literature review. Irish Journal of Psychological Medicine , 31 , (4) , pp. 281-286.

Scanlon, Adrian (2014) Pregabalin for detoxification from opioids: a single case study. Mental Health and Substance Use , 7 , (4) , pp. 263-285.

Drug and Alcohol Findings. (2012) Effectiveness Bank Bulletin [Methamphetamine treatment]. Effectiveness Bank Bulletin , 28 Nov .

Behan, Aine and Hryniewiecka, Magdalena and O'Tuathaigh, Colm MP and Kinsella, Anthony and Cannon, Mary and Karayiorgou, Maria and Gagos, Joseph A and Waddington, John L and Cotter, David R (2012) Chronic adolescent exposure to Delta-9-Tetrahydrocannabinol in COMT mutant mice: impact on indices of dopaminergic, endocannabinoid and GABAergic pathways. Neuropsychopharmacology , 37 , pp. 1773-1783.

Report

McClements, Anne Marie and Scarlett, Mary and Stewart, Bill (2024) Statistics from the Northern Ireland substance misuse database: 1 April 2022 – 31 March 2023. Belfast: Northern Ireland. Department of Health.

McNamara, Sinead and Killeen, Nicki and Eagleton, Marie and Keenan, Eamon (2023) HSE emerging drug trend monitoring. Year 2 results from the Syringe Analysis Programme 2022. The identification of injecting trends in the Dublin and Midland Region through the application of syringe analysis methodology. Dublin: Health Service Executive.

National Working Group for Dual Diagnosis. (2023) Model of care for people with mental disorder and co-existing substance use disorder (dual diagnosis). Dublin: Health Service Executive.

International Narcotics Control Board. (2023) Report of the International Narcotics Control Board for 2022. Vienna: United Nations.

United Nations Office on Drugs and Crime. (2023) UN convention decisions 1961 - 2022. Vienna: United Nations Office on Drugs and Crime.

McNamara, Sinead and Killeen, Nicki and Stokes, Siobhan and Keenan, Eamonn (2022) Irish syringe analysis pilot project. Dublin: HSE National Social Inclusion Office.

Public Health Scotland. (2022) The national drug-related deaths database (Scotland) report. Public Health Scotland.

National Institute for Health and Care Excellence. (2022) Medicines associated with dependence or withdrawal symptoms: safe prescribing and withdrawal management for adults. London: National Institute for Health and Care Excellence.

Office for National Statistics. (2021) Deaths related to drug poisoning in England and Wales: 2020 registrations. London: Office for National Statistics.

Public Health England. (2021) Drug Harms Assessment and Response Team. Quarterly summary for professionals: May 2021. London: Public Health England.

Foster, Cyrss and Scarlett, Mary and Stewart, Bill (2020) Young persons’ behaviour and attitudes survey 2019: substance use - (smoking, alcohol & drugs). Belfast: Department of Health.

Duffin, Tony and Keane, Marcus and Millar, Sean R (2020) Street tablet use in Ireland: a Trendspotter study on use, markets, and harms. Dublin: Ana Liffey Drug Project.

Canadian Coalition for Seniors’ Mental Health. (2019) Canadian guidelines on benzodiazepine receptor agonist use disorder among older adults. Toronto: Canadian Coalition for Seniors’ Mental Health.

Taylor, Stephen and Annand, Fizz and Burkinshaw, Peter and Greaves, Felix and Kelleher, Michael and Knight, Jonathan and Perkins, Clare and Tran, Anh and White, Martin and Marsden, John (2019) Dependence and withdrawal associated with some prescribed medicines. An evidence review. London: Public Health England.

WHO Expert Committee on Drug Dependence. (2017) 39th Expert Committee on Drug Dependence: technical documents. Geneva: World Health Organization.

Extern. (2017) Pregabalin: Guidance for people working with Pregabalin users. Newtownabbey: Extern.

Webpage

WHO Expert Committee on Drug Dependence. (2023) Expert Committee on Drug Dependence information repository. URL: https://ecddrepository.org/en

FactSheet

Simon Community Scotland, Public Health Scotland. (2024) How to save a life: emergency response to a drug overdose, and harm reduction advice. Edinburgh: Public Health Scotland.

HRB National Drugs Library. (2023) Factsheet: Opioids - the Irish situation. Dublin: HRB National Drugs Library.

Organization of Teratology Information Specialists. (2022) Mother to baby: fact sheets [Internet]. Brentwood (TN): Organization of Teratology Information Specialists.

Health Service Executive. (2020) Appropriate prescribing of Pregabalin. Dublin: Health Service Executive.

UK Teratology Information Service. (2019) BUMPS: Best use of medicines in pregnancy - Gabapentin. London: UK Teratology Information Service.

Drugs.ie. (2017) Pregabalin factsheet. Dublin: drugs.ie.

UK Teratology Information Service. (2016) BUMPS: Best use of medicines in pregnancy - Pregabalin. London: UK Teratology Information Service.

Dail Debates

[Oireachtas] Dáil Éireann debate. Question 509 - Medicinal products [Pregabalin] [40993/23]. (26 Sep 2023)

[Oireachtas] Dáil Éireann debate. Question 970 – Medicinal products. [pregabalin-related deaths] [40177/23]. (20 Sep 2023)

[Oireachtas] Dáil Éireann debate. Written answer 65 - Medicinal products [Pregabalin] [18539/23]. (20 Apr 2023)

[Oireachtas] Dáil Éireann debate. Written answer 577 - Substance misuse [56590/22]. [Pregabalin deaths]. (15 Nov 2022)

[Oireachtas] Dail Eireann debates. Written answers 325, 326, 327 & 328 - Medicinal products regulation [6693/18]. (13 Feb 2018)

[Oireachtas] Dail Eireann debate. Written answer 36 - Prescriptions data [Opioids and sedatives] [37968/16]. (01 Dec 2016)

[Oireachtas] Dail Eireann debate. Written answer 660 - Prescriptions data [Pregabalin] [22587/16]. (19 Jul 2016)

Conference or Workshop Item

Citywide. (2020) Current trends in drug use presentations. In: Current trends in drug use, 18 November 2020, Webinar.

Santlal, Kiran and Gibbons, Zorina and McCarron, Peter and Keenan, Eamon (2017) Gamma Hydroxybutyrate & Gamma Butrolactone (GHB/GBL): a case series of inpatient & outpatient detoxification. In: Club Health Dublin, 24-26 June 2017, Dublin.

Thesis

Lynn, Ena (2022) Drug poisoning deaths among women in Ireland. PhD thesis, Royal College of Surgeons in Ireland.

Teaching Resource

Statspearl. (2022) StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing.

News

[Irish Times] , Cullen, Paul ‘Coffin tablet’: Renewed calls for prescription drug feared to be ‘new OxyContin’ to be reclassified. (25 Feb 2024)

[Irish Times] , Carolan, Mary Coroners call for prescription medication nicknamed ‘coffin tablets’ to be reclassified as controlled drug. (19 Mar 2023)

[Irish Times] , Gallagher, Conor Over-prescription of tablets helping to drive illicit street trade. (28 Apr 2020)

[Irish Times] , Houston, Muiris Benzodiazepine warning is highly significant. (30 Sep 2019)

[BBC News Northern Ireland] , Bonner, Kelly [Northern Ireland] Pregabalin/Lyrica reclassified to a class C drug. (01 Apr 2019)

[Irish Times] The Irish Times view on deaths from prescription drugs: cause for alarm. (14 Mar 2019)

[thejournal.ie] , Thomas, Conal From medicine cabinet to the streets: Abuse of prescription drugs rises in Dublin. (22 Feb 2019)

[BMJ] UK Pregabalin and gabapentin become controlled drugs to cut deaths from misuse. (16 Oct 2018)

[Belfast Media Group] , Short, Evan [Northern Ireland].Hydebank: Drugs are easier to get inside teenagers’ jail than outside. (06 Oct 2017)

[drugs.ie] Pregabalin harm reduction campaign launched on drugs.ie. (22 Mar 2017)

[Derry Journal] , Mullan, Kevin Pfizer seeking testimony from illegal pill users as part of drug surveillance efforts. (15 Jan 2017)

[Department of Health (UK)] [Northern Ireland] Department of Health warning over illicit prescription drugs in circulation. (23 Dec 2016)

[Belfast Telegraph] Drug 'important therapeutic agent'. [Pregabalin]. (26 Sep 2014)

[European Parliament] New psychoactive substances: European Parliament committee backs Commission proposal. (11 Mar 2014)

This list was generated on Fri Mar 29 04:30:32 2024 GMT.