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Home > Methylenedioxymethamphetamine (MDMA, 'Ecstasy'): a stressor on the immune system.

Connor, TJ (2004) Methylenedioxymethamphetamine (MDMA, 'Ecstasy'): a stressor on the immune system. Immunology , 111 , (4) , pp. 357-367.

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Drug abuse is a global problem impacting on health. One such health concern stems from the fact that many drugs of abuse have immunosuppressive actions and consequently have the potential to increase susceptibility to infectious disease. This article is focused on the impact of the amphetamine derivative, methylenedioxymethamphetamine (MDMA; 'Ecstasy') on immunity. Research conducted over the last five years, in both laboratory animals and humans, has demonstrated that MDMA has immunosuppressive actions. As many of the physiological changes elicited by MDMA closely resemble those induced by acute stress, it is suggested that exposure to MDMA could be regarded as a 'chemical stressor' on the immune system. Finally, the potential of MDMA-induced immunosuppression to translate into significant health risks for abusers of the drug will be discussed.

 

Item Type
Article
Date
2004
Call No
BJ2.8, XT
Page Range
pp. 357-367
Publisher
Wiley-Blackwell
Volume
111
Number
4
Keywords
AOD induced risk, health risk assessment, immune system, immunosuppressive agents, Ireland, MDMA, stressor
EndNote
Accession Number
HRB 2734 (Electronic Only)
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