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Home > Increased severity and morbidity of acute hepatitis in drug abusers with simultaneously acquired hepatitis B and hepatitus D virus infections.

Shattock, Alan G and Irwin, Fiona M and Morgan, Bridget M and Hillary, Irene B and Kelly, Michael G and Fielding, JF and Kelly, Deirdre A and Weir, Donald G (1985) Increased severity and morbidity of acute hepatitis in drug abusers with simultaneously acquired hepatitis B and hepatitus D virus infections. British Medical Journal, 290, (6479), pp. 1377-1380.

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Superinfection of carriers of hepatitis B virus by hepatitis virus (delta agent) may produce more severe hepatitis, and lead to chronic active hepatitis and cirrhosis, more often than with hepatitis B infection alone. An outbreak of hepatitis B and hepatitis D virus infections among drug abusers in Dublin started in late 1980. This provided the opportunity to investigate the role of the hepatitis D virus in exacerbating acute hepatitis, when hepatitis B and D viruses were acquired simultaneously. This study found increased severity and morbidity of acute hepatitis in drug abusers with simultaneous acquisition of the hepatitis B and D virus infections.


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