Home > Selecting for potency: are drug controls shaping the evolution of illicit drug markets?

Moore, R and Treble, R and Wood, R and Hudson, S and Lawson, A J and Copeland, C S (2026) Selecting for potency: are drug controls shaping the evolution of illicit drug markets? International Journal of Drug Policy, 158, 105536. https://doi.org/10.1016/j.drugpo.2026.105536.

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Since the late 2000s, illicit drug markets have been characterised by a seemingly endless succession of highly potent novel psychoactive substances (NPS) (Shafi et al., 2020). This phenomenon is commonly attributed to illicit innovation outpacing drug control systems (Seddon, 2014). Yet the possibility that drug controls may unintentionally promote the emergence of more potent substances – the so-called "potency paradox" – has been recognised for decades (Thornton, 1998). Here, we examine recent UK developments as a contemporary illustration of this longstanding hypothesis...

Item Type
Article
Publication Type
International, Open Access, Article
Drug Type
Substances (not alcohol/tobacco), New psychoactive substance
Intervention Type
Harm reduction, Screening / Assessment
Date
16 October 2026
Identification #
https://doi.org/10.1016/j.drugpo.2026.105536
Publisher
Elsevier
Volume
158
EndNote

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