Ketamine seizures increased year-on-year in Scotland from 2018 to 2024; the number of seizures was six times higher in 2024 compared to 2018 and concentrated within Greater Glasgow, Edinburgh, and the North East regions. Seizures in Greater Glasgow continue to rise rapidly with indications that this is a key area for ketamine supply and distribution. On average, 70% of seized ketamine samples contained only ketamine, while 30% were mixed with other substances. These mixtures can increase the risk of unexpected or harmful effects, making it important to know that the ketamine is pure rather than mixed with other drugs. Most seized ketamine was white or crystalline powder, which may look like and be confused with substances such as medetomidine or xylazine. For people who use drugs, a major challenge in identifying ketamine is the lack of reliable, easy-to-use tests for drug checking. Colour-changing tests remain the most viable commercial option, though several new test strip designs may be effective drug checking tools in the future.