The report shows that 2025 marked a decisive escalation in alcohol industry interference. As alcohol sales stagnated in key markets, awareness of alcohol’s role in cancer and other noncommunicable diseases expanded, and younger generations increasingly rejected alcohol, multinational alcohol corporations responded not by changing their business models, but by consolidating a global system of influence designed to preserve affordability, availability, and attractiveness of alcohol. This pattern is detailed in this report. It reveals how commercial vulnerability translated directly into intensified political interference across countries, institutions, and policy arenas.