Ulisse, Krista and Albitar, Jehad and Aromin, Jourdan T and Berry, James (2025) Emerging interventions in behavioral addictions: a narrative review of psychedelics and neuromodulation. Brain Sciences, 15, (9), 980. https://doi.org/10.3390/brainsci15090980.
External website: https://www.mdpi.com/2076-3425/15/9/980
Addiction remains a persistent public health crisis, marked by poor treatment retention and limited pharmacotherapy options. Emerging treatments, such as psychedelic-assisted psychotherapy and neuromodulation, offer promising avenues for circuit-level interventions in behavioral addictions. This narrative review synthesizes the current landscape of psychedelic compounds and neuromodulation techniques with a focus on their mechanisms of action, applications in specific behavioral addictions, and translational potential. By targeting disrupted reward, executive control, and stress regulation networks, these interventions may facilitate meaningful recovery and long-term remission in otherwise treatment refractory cases. We highlight key findings, current research limitations, and future directions in integrating these novel therapies into the treatment of gambling disorder; internet gaming disorder/gaming disorder, predominantly online; internet use disorder; and compulsive sexual behavior disorder.
F Concepts in psychology > Process / behavioural disorder (addiction) > Gambling
F Concepts in psychology > Process / behavioural disorder (addiction) > Process disorder treatment or recovery
F Concepts in psychology > Process / behavioural disorder (addiction) > Gaming disorder / problem
F Concepts in psychology > Process / behavioural disorder (addiction) > Internet / Phone disorder
F Concepts in psychology > Behaviour > Choice-making / reward behaviour
VA Geographic area > International
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