This report provides an update of information contained in earlier reports of the "Multi-city Study of Drug Misuse" for the years 1986 and 1989. Information already presented showed the occurrence of an opiate epidemic in Dublin, which commenced in the late 1970s reaching a peak in 1983. Data since then particularly relating to the indicators, first treatment demand, viral hepatitis, police arrests and seizures of illicit drugs point to a reduction and stabilisation of drug misuse in the city. Heroin remains 'the preferred drug of misuse.