Home > Nurse care management for opioid use disorder treatment: the PROUD cluster randomized clinical trial.

Wartko, Paige D and Bobb, Jennifer F and Boudreau, Denise M and Matthews, Abigail G and McCormack, Jennifer and Lee, Amy K and Qiu, Hongxiang and Yu, Onchee and Hyun, Noorie and Idu, Abisola E and Campbell, Cynthia I and Saxon, Andrew J and Liu, David S and Altschuler, Andrea and Samet, Jeffrey H and Labelle, Colleen T and Zare-Mehrjerdi, Mohammad and Stotts, Angela L and Braciszewski, Jordan M and Murphy, Mark T and Dryden, Douglas and Arnsten, Julia H and Cunningham, Chinazo O and Horigian, Viviana E and Szapocznik, José and Glass, Joseph E and Caldeiro, Ryan M and Phillips, Rebecca C and Shea, Mary and Bart, Gavin and Schwartz, Robert P and McNeely, Jennifer and Liebschutz, Jane M and Tsui, Judith I and Merrill, Joseph O and Lapham, Gwen T and Addis, Megan and Bradley, Katharine A and Ghiroli, Megan M and Hamilton, Leah K and Hu, Yong and LaHue, Jennifer S and Loree, Amy M and Murphy, Sean M and Northrup, Thomas F and Shmueli-Blumberg, Dikla and Silva, Angela J and Weinstein, Zoe M and Wong, Mark TinFook and Burganowski, Rachael P (2023) Nurse care management for opioid use disorder treatment: the PROUD cluster randomized clinical trial. JAMA Internal Medicine, 183, (12), pp. 1343-1354. 10.1001/jamainternmed.2023.5701.

External website: https://jamanetwork.com/journals/jamainternalmedic...

Importance: Few primary care (PC) practices treat patients with medications for opioid use disorder (OUD) despite availability of effective treatments.

Question: Does adding a nurse care manager to support opioid use disorder (OUD) medication treatment in primary care (PC) increase OUD treatment?

Findings: In this cluster randomized clinical trial across 6 diverse health systems in 5 US states, when compared with usual care clinics, intervention clinics provided substantially more OUD treatment (8.2 more patient-years of OUD treatment per 10 000 PC patients). Increases in OUD treatment appeared limited to patients new to PC clinics or newly treated for OUD post-randomization and varied by system.

Meaning: Adding a nurse care manager to PC to support OUD treatment increases potentially lifesaving medication treatment for OUD.


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