Walton, Sara E and Wilks, Justin and Denn, Max T and Quinter, Alexis D and DeBord, Joshua and Logan, Barry K and Krotulski, Alex J (2024) MMB-4en-PINACA — NPS Discovery new drug monograph. United States: Center for Forensic Science Research and Education.
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The following information was compiled in June 2024 and is subject to change as new research is conducted and as new information becomes available:
Description: MMB-4en-PINACA is a novel synthetic cannabinoid with structural similarity to MDMB-4en-PINACA, MMB-4en-PICA, and other synthetic cannabinoids. MMB-4en-PINACA was first detected in February 2024 by our laboratory and was confirmed in comparison to standard reference material.
Sample Source: Cook County Sheriff’s Office (Chicago, IL)
Sample Appearance: Paper samples
Pharmacology: In vitro pharmacological data available for MMB-4en-PINACA show that this synthetic cannabinoid is active but less potent than its tert-leucine counterpart MDMB-4en-PINACA.1
Toxicology: MMB-4en-PINACA has not yet been identified in toxicology cases to date at the CFSRE.
Drug Materials: MMB-4en-PINACA has been detected in two drug materials to date at the CFSRE.
Demographics / Geographics: Drug materials originated from Chicago, Illinois. MMB-4en-PINACA was found in the absence of other drugs in one case and alongside MDMB-4en-PINACA in one case.
Legal Status: MMB-4en-PINACA is not currently scheduled in the United States.
Class: Cannabinoid
Appearance: Paper
Formula: C19H25N3O3
MW: 343.42 [M+]: 343 [M+H]+: 344.1969
IUPAC: Methyl 3-methyl-2-[(1-pent-4-enylindazole-3-carbonyl)amino]butanoate
Report Date: June 20, 2024
B Substances > New (novel) psychoactive substances > Synthetic cannabinoids (Spice / K2 / OXIZID / HHC)
E Concepts in biomedical areas > Pharmacology and toxicology
J Health care, prevention, harm reduction and treatment > Risk and needs assessment > Risk assessment
VA Geographic area > United States
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