Home > Opioid overdose after medication for opioid use disorder initiation following hospitalization or ED visit.

Weiner, Scott G and Little, Kacey and Yoo, Jiah and Flores, Diana P and Hildebran, Christi and Wright, Dagan A and Ritter, Grant A and El Ibrahimi, Sanae (2024) Opioid overdose after medication for opioid use disorder initiation following hospitalization or ED visit. JAMA Network Open, 7, (7), e2423954. 10.1001/jamanetworkopen.2024.23954.

External website: https://jamanetwork.com/journals/jamanetworkopen/f...

Importance: Hospitalizations related to opioid use disorder (OUD) represent an opportunity to initiate medication for OUD (MOUD).

Question: Is starting medication for opioid use disorder (OUD) treatment after a hospital visit associated with lower odds of future fatal or nonfatal opioid overdose?

Findings: In this cohort study of 22 235 patients with an OUD-related hospital visit, 5.3% commenced medication for OUD within 7 days, and these patients had lower adjusted odds of fatal or nonfatal opioid overdose at 6 months.

Meaning: The findings suggest that hospital visits are an opportunity to initiate medication for OUD and are associated with lower odds of opioid overdose at 6 months.


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