Home > A review of the evidence on the use and harms of xylazine, medetomidine and detomidine.

Advisory Council on the Misuse of Drugs. (2024) A review of the evidence on the use and harms of xylazine, medetomidine and detomidine. London: Advisory Council on the Misuse of Drugs.

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This report reviews the evidence of use and the harms of xylazine in the UK and considers whether it should be controlled by the Misuse of Drugs Act 1971. Evidence of Illicit use in the UK of the related compounds medetomidine and detomidine was also sought, as this has been reported in other countries.

The report provides recommendations for the classification and scheduling of xylazine, following a thorough review of the evidence available.

[See also, UK Government response to the ACMD’s advice on xylazine and related compounds, published 21 March 2024]

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