The National Cancer Registry of Ireland is now in its 30th year of data collection, and in our 2023 annual statistical report, we summarise cancer data collected up to diagnosis year 2021 with provisional figures for 2022. In addition to the more regular reporting of incidence, mortality and prevalence figures, this year we are focusing on the impact of age and stage at diagnosis on cancer outcomes as well providing updates on the proportion of cancer cases presenting emergently. As with previous years, we are also presenting updated data on the impact of the COVID-19 pandemic on numbers of cancers diagnosed.