Whitley, Penn and LaRue, Leah and Fernandez, Soledad A and Passik, Steven D and Dawson, Eric and Jackson, Rebecca D (2022) Analysis of urine drug test results from substance use disorder treatment practices and overdose mortality rates, 2013-2020. JAMA Network Open, 5, (6), e2215425. 10.1001/jamanetworkopen.2022.15425.
External website: https://jamanetwork.com/journals/jamanetworkopen/f...
Question: Do urine drug test (UDT) results correlate with overdose mortality rates?
Findings: In this cross-sectional study of 500 000 unique urine specimens collected from substance use disorder treatment practices, UDT results for 5 drug categories were correlated with overdose mortality rates at national, state, and county levels. Correlation was strongest for synthetic opioids and methamphetamine, and multivariate regression analysis using state-level data revealed that synthetic opioid and methamphetamine UDT positivity rates were significantly associated with overdose deaths.
Meaning: This study’s findings suggest that UDT is a valuable data source that is capable of informing real-time surveillance efforts.
E Concepts in biomedical areas > Pharmacology and toxicology
G Health and disease > Substance use disorder > Multiple substance use (Poly-drug /Poly-substance)
G Health and disease > Substance use disorder > Drug use disorder > Drug intoxication > Poisoning (overdose)
HA Screening, identification, and diagnostic method > Medical screening, assessment and diagnostic method
J Health care, prevention, harm reduction and treatment > Identification and screening > Identification and screening for substance use
P Demography, epidemiology, and history > Population dynamics > Substance related mortality / death
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