Jarlenski, Marian and Chen, Qingwen and Gao, Alice and Rothenberger, Scott D and Krans, Elizabeth E (2022) Research letter: Association of duration of methadone or buprenorphine use during pregnancy with risk of nonfatal drug overdose among pregnant persons with opioid use disorder in the US. JAMA Network Open, 5, (4), e227964. doi: 10.1001/jamanetworkopen.2022.7964.
External website: https://jamanetwork.com/journals/jamanetworkopen/f...
Opioid use disorder (OUD) is associated with morbidity and mortality during pregnancy and post partum, and emerging evidence suggests that drug-related deaths are a leading cause of mortality. Although pregnant persons with OUD are at high risk of drug overdose events during pregnancy and postpartum, medication for OUD (MOUD) may mitigate adverse outcomes by reducing illicit drug use and facilitating engagement with health care professionals to address co-occurring chronic conditions. Our objective was to quantify the association of the duration of MOUD use during pregnancy and the risk of nonfatal overdose in pregnancy among pregnant persons with OUD in the US.....
E Concepts in biomedical areas > Pregnancy
G Health and disease > Substance use disorder > Drug use disorder > Drug intoxication > Poisoning (overdose)
HJ Treatment or recovery method > Substance disorder treatment method > Substance replacement method (substitution) > Opioid agonist treatment (methadone maintenance / buprenorphine)
J Health care, prevention, harm reduction and treatment > Patient / client care management
T Demographic characteristics > Pregnant woman
VA Geographic area > United States
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