Merlin, Jessica S and Khodyakov, Dmitry and Arnold, Robert and Bulls, Hailey W and Dao, Emily and Kapo, Jennifer and King, Caroline and Meier, Diane and Paice, Judith and Ritchie, Christine and Liebschutz, Jane M (2021) Expert panel consensus on management of advanced cancer-related pain in individuals with opioid use disorder. JAMA Network Open, 4, (12), e2139968. doi: 10.1001/jamanetworkopen.2021.39968.
External website: doi: 10.1001/jamanetworkopen.2021.39968
Question: What is the consensus of experts in palliative care, addiction, or both on the appropriateness of strategies to manage advanced cancer–related pain in individuals with co-occurring opioid use disorder?
Findings: In this qualitative study, experts deemed it appropriate to continue medication for opioid use disorder (buprenorphine-naloxone or methadone) and to dose methadone outside the context of a methadone clinic 3 times per day. The appropriateness of adding full agonist opioids to either buprenorphine-naloxone or methadone depended on prognosis.
Meaning: This study provides urgently needed, consensus-based guidance for clinicians and highlights critical research and policy gaps needed to facilitate implementation.
E Concepts in biomedical areas > Medical substance > Prescription drug (medicine / medication)
G Health and disease > Substance use disorder > Drug use disorder
G Health and disease > Pathologic process > Cancer
J Health care, prevention, harm reduction and treatment > Patient / client care management
J Health care, prevention, harm reduction and treatment > Treatment and maintenance > Treatment issues (pain management)
VA Geographic area > United States
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