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Home > Association of new perioperative benzodiazepine use with persistent benzodiazepine use.

Wright, Jason D and Cogan, Jacob C and Huang, Yongmei and Tergas, Ana I and St Clair, Caryn M and Hou, June Y and Khoury-Collado, Fady and Gockley, Allison and Accordino, Melissa and Melamed, Alexander and Hershman, Dawn L (2021) Association of new perioperative benzodiazepine use with persistent benzodiazepine use. JAMA Network Open, 4, (6), e2112478. doi: 10.1001/jamanetworkopen.2021.12478.

External website: https://jamanetwork.com/journals/jamanetworkopen/f...

Question: How frequently are benzodiazepines prescribed and used persistently among patients undergoing surgery?

Findings: In this cohort study of more than 2.5 million patients who underwent 1 of 11 surgical procedures from 2009 to 2017, benzodiazepines were prescribed for 2.6% of patients. Among benzodiazepine-naive patients prescribed a perioperative benzodiazepine, the rate of persistent benzodiazepine use was 19.5%.

Meaning: While a relatively small percentage of surgical patients in this cohort study were prescribed benzodiazepines in the perioperative period, 1 in 5 of these patients went on to persistent benzodiazepine use.


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