Invited commentary:
Although the US has seen a decrease in opioid misuse rates among adolescents and young adults since 2015, opioid use disorder and overdose remain major public health problems in this high-risk population. Data from the US Substance Abuse and Mental Health Services Administration estimate that in 2018, 5.6% of young adults aged 18 to 25 years and 2.8% of adolescents aged 12 to 17 years misused prescription opioids in the past year.1 The reasons for high substance use rates in this age group are complex but include many factors rooted in neurodevelopment, socioeconomic characteristics, peer groups, and family life.........