Home > Take-home naloxone.

European Monitoring Centre for Drugs and Drug Addiction. (2019) Take-home naloxone. Lisbon: EMCDDA.

URL: http://www.emcdda.europa.eu/publications/topic-ove...

What is naloxone and why is it important?

Drug overdose continues to be the main cause of death among problem drug users. Heroin or other opioids — often consumed alongside other central nervous system depressants such as benzodiazepines and alcohol — are present in the majority of reported fatal overdoses. Overdose is common among opioid users: many of them have experienced a non-fatal overdose and most have witnessed one. Death from opioid overdose is caused primarily by respiratory depression leading to cardiac arrest.


Opioid overdose deaths can be prevented through timely administration of naloxone, a potent opioid antagonist drug that rapidly reverses the effects of opioid analgesics by binding to the opioid receptors in the central nervous system (see Spotlight: Naloxone). Because of its effectiveness, naloxone is used by emergency personnel worldwide.


[Under country profiles: click on Ireland for brief information]

Item Type:Evidence resource
Drug Type:Opioid
Intervention Type:AOD disorder, AOD disorder harm reduction
Date:August 2019
Corporate Creators:European Monitoring Centre for Drugs and Drug Addiction
Place of Publication:Lisbon
Subjects:B Substances > Opioids (opiates)
B Substances > Opioids (opiates) > Opioid product > Naloxone
G Health and disease > Substance use disorder > Drug use > Drug intoxication > Poisoning (overdose)
J Health care, prevention and rehabilitation > Substance use prevention > Substance use harm reduction
VA Geographic area > Europe
VA Geographic area > Europe > Ireland

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