Home > Perioperative alcohol cessation intervention for postoperative complications.

Egholm, Julie WM and Pederson, Bolette and Moller, Ann Merete and Adami, Johanna and Juhl, Carsten B and Tonnesen, Hanne (2018) Perioperative alcohol cessation intervention for postoperative complications. Cochrane Database of Systematic Reviews, (11), Art. No.: CD008343. DOI: 10.1002/14651858.CD008343.pub3..

External website: https://www.cochranelibrary.com/cdsr/doi/10.1002/1...

This systematic review assessed the efficacy of perioperative alcohol cessation interventions for postoperative complications and alcohol consumption. All three studies showed a significant reduction in the number of participants who quit drinking alcohol during the intervention period. Intensive alcohol cessation interventions offered for four to eight weeks to participants undergoing all types of surgical procedures to achieve complete alcohol cessation before surgery probably reduced the number of postoperative complications. Data were insufficient for review authors to assess their effects on postoperative mortality. No studies reported an effect on length of stay, and no studies addressed the prevalence of risky drinking in the longer term.

Included studies were few and reported small sample sizes; therefore one should be careful about drawing firm conclusions based on these study results. All three studies were conducted in Denmark, and most participants were men. The included participants may represent a selective group, as they could have been more motivated and/or more interested in participating in clinical research or otherwise different, and effects may have been overestimated for both intervention and control groups in these studies. Trial results indicate that these studies are difficult to perform, that strong research competencies are necessary for future studies, and that further evaluation of perioperative alcohol cessation interventions in high‐quality randomized controlled trials is needed. Once published and assessed, the one 'ongoing' study identified may alter the conclusions of this review.

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