Magalhães, Pedro V [The Cochrane Library] . (2014) Clinical question: What are the benefits and harms of buprenorphine maintenance versus placebo or methadone maintenance in people with opioid dependence? London: Wiley. Cochrane Clinical Answers
URL: https://www.cochranelibrary.com/cca/doi/10.1002/cc...
Buprenorphine, a partial opioid agonist, has pharmacological features, including safety at overdose and ease of use, which make it an interesting alternative to methadone for those with heroin use disorders. However, buprenorphine maintenance, although effective compared with placebo, was inferior to methadone in retaining people in treatment. There were no clear differences between the drugs on the other primary outcomes (drug use, safety, criminal activity).
| Field | Value |
|---|---|
| Item Type: | Evidence resource |
| Publication Type: | Guideline |
| Drug Type: | Opioid |
| Intervention Type: | AOD disorder, AOD disorder drug therapy, AOD disorder treatment method |
| Source: | The Cochrane Library |
| Date: | 25 November 2014 |
| Publisher: | Wiley |
| Place of Publication: | London |
| EndNote: | View |
| Subjects: | A Substance use, abuse, and dependence > Effects and consequences B Substances > Opioids (opiates) B Substances > Opioids (opiates) > Opioid product B Substances > Opioids (opiates) > Opioid product > Buprenorphine / Suboxone B Substances > Opioids (opiates) > Opioid product > Methadone HJ Treatment method > Substance disorder treatment method HJ Treatment method > Substance disorder treatment method > Substance disorder drug therapy HJ Treatment method > Treatment outcome J Health care, prevention and rehabilitation > Patient care management N Communication, information and education > Recommendations or guidelines > Practice / clinical guidelines |
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