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Home > Clinical question: How do alpha2‐adrenergic agonists compare with placebo or methadone for management of opioid withdrawal?

Burch, Jane and Magalhães, Pedro V (2017) Clinical question: How do alpha2‐adrenergic agonists compare with placebo or methadone for management of opioid withdrawal? Cochrane Clinical Answers, .

External website: https://www.cochranelibrary.com/cca/doi/10.1002/cc...

Alpha2‐adrenergic agonists may be beneficial for controlling symptoms of opioid withdrawal. However, when compared with reduced doses of methadone, retention may be worse and risk of adverse events greater with alpha2‐adrenergic agonists....


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