Home > Clinical question: How do alpha2‐adrenergic agonists compare with placebo or methadone for management of opioid withdrawal?

Burch, Jane and Magalhães, Pedro V [The Cochrane Library] . (2017) Clinical question: How do alpha2‐adrenergic agonists compare with placebo or methadone for management of opioid withdrawal? London: Wiley. Cochrane Clinical Answers

URL: https://www.cochranelibrary.com/cca/doi/10.1002/cc...

Alpha2‐adrenergic agonists may be beneficial for controlling symptoms of opioid withdrawal. However, when compared with reduced doses of methadone, retention may be worse and risk of adverse events greater with alpha2‐adrenergic agonists....


Item Type:Evidence resource
Publication Type:Guideline
Drug Type:Opioid
Intervention Type:AOD disorder, AOD disorder drug therapy, AOD disorder treatment method
Source:The Cochrane Library
Date:4 July 2017
Publisher:Wiley
Place of Publication:London
EndNote:View
Subjects:B Substances > Opioids (opiates)
B Substances > Opioids (opiates) > Opioid product
B Substances > Opioids (opiates) > Opioid product > Methadone
G Health and disease > Substance use disorder > Drug use > Drug withdrawal syndrome
HJ Treatment method > Substance disorder treatment method
HJ Treatment method > Substance disorder treatment method > Substance disorder drug therapy
HJ Treatment method > Treatment outcome
J Health care, prevention and rehabilitation > Patient care management
N Communication, information and education > Recommendations or guidelines > Practice / clinical guidelines

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