Burch, Jane and Magalhães, Pedro V (2017) Clinical question: How does buprenorphine compare with methadone or adrenergic agonists in people undergoing opioid withdrawal? Cochrane Clinical Answers,
External website: https://www.cochranelibrary.com/cca/doi/10.1002/cc...
Buprenorphine seems to provide benefits over adrenergic agonists in terms of reduction of withdrawal symptoms and retention in treatment, with a similar adverse event profile. When compared with methadone, buprenorphine seems as effective, but analyses included few people and none of the evidence was high quality.
B Substances > Opioids (opiates) > Opioid product
B Substances > Opioids (opiates) > Opioid product > Buprenorphine / Suboxone
B Substances > Opioids (opiates) > Opioid product > Methadone
G Health and disease > Substance use disorder (addiction) > Drug use disorder > Drug withdrawal / craving
HJ Treatment or recovery method > Substance disorder treatment method > Substance disorder drug therapy (pharmacological treatment)
HJ Treatment or recovery method > Substance disorder treatment method > Substance replacement method (substitution) > Opioid agonist treatment (methadone maintenance / buprenorphine)
HJ Treatment or recovery method > Treatment outcome
J Health care, prevention, harm reduction and treatment > Patient / client care management
N Communication, information and education > Recommendations > Practice / clinical guidelines
VA Geographic area > International
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