Home > Clinical question: How does buprenorphine compare with methadone or adrenergic agonists in people undergoing opioid withdrawal?

Burch, Jane and Magalhães, Pedro V [The Cochrane Library] . (2017) Clinical question: How does buprenorphine compare with methadone or adrenergic agonists in people undergoing opioid withdrawal? London: Wiley. Cochrane Clinical Answers

URL: https://www.cochranelibrary.com/cca/doi/10.1002/cc...

Buprenorphine seems to provide benefits over adrenergic agonists in terms of reduction of withdrawal symptoms and retention in treatment, with a similar adverse event profile. When compared with methadone, buprenorphine seems as effective, but analyses included few people and none of the evidence was high quality.


Item Type:Evidence resource
Publication Type:Guideline
Drug Type:Opioid
Intervention Type:AOD disorder, AOD disorder drug therapy, AOD disorder treatment method
Source:The Cochrane Library
Date:28 August 2017
Publisher:Wiley
Place of Publication:London
EndNote:View
Subjects:B Substances > Opioids (opiates)
B Substances > Opioids (opiates) > Opioid product
B Substances > Opioids (opiates) > Opioid product > Buprenorphine / Suboxone
B Substances > Opioids (opiates) > Opioid product > Methadone
G Health and disease > Substance use disorder > Drug use > Drug withdrawal syndrome
HJ Treatment method > Substance disorder treatment method > Substance disorder drug therapy
HJ Treatment method > Treatment outcome
J Health care, prevention and rehabilitation > Patient care management
N Communication, information and education > Recommendations or guidelines > Practice / clinical guidelines

Repository Staff Only: item control page