Home > Clinical question: For people with opioid dependence, does supervised dosing of their long‐acting opioid substitution medication help to improve outcomes?

Burch, Jane and Tort, Sera [The Cochrane Library] . (2017) Clinical question: For people with opioid dependence, does supervised dosing of their long‐acting opioid substitution medication help to improve outcomes? London: Wiley. Cochrane Clinical Answers

URL: https://www.cochranelibrary.com/cca/doi/10.1002/cc...

Compared with unsupervised consumption of a long‐acting opioid substitution medication or routine counseling for people with opioid dependence, supervising the consumption of a long‐acting opioid substitution medication did not have a clear impact on the numbers of people completing the study protocol (retention), nor in the numbers of people staying abstinent from unsanctioned opioid use, engaging in inappropriate medication use (such as selling or sharing medication), or dying or experiencing any other serious adverse event. However, all the randomized controlled trial evidence was of very low to low quality, so no firm conclusions of equivalence between unsupervised and supervised consumption can be made.


Item Type:Evidence resource
Publication Type:Guideline
Drug Type:Opioid
Intervention Type:AOD disorder, AOD disorder drug therapy, AOD disorder treatment method, AOD disorder harm reduction, Psychosocial treatment method
Source:The Cochrane Library
Date:22 November 2017
Publisher:Wiley
Place of Publication:London
EndNote:View
Subjects:B Substances > Opioids (opiates)
B Substances > Opioids (opiates) > Opioid product
F Concepts in psychology > Specific attitude and behaviour > choice-making behaviour
HJ Treatment method > Substance disorder treatment method
HJ Treatment method > Substance disorder treatment method > Substance disorder drug therapy
HJ Treatment method > Substance disorder treatment method > Substance replacement method (substitution)
HJ Treatment method > Treatment outcome
J Health care, prevention and rehabilitation > Patient care management
J Health care, prevention and rehabilitation > Treatment and maintenance > Treatment factors
N Communication, information and education > Recommendations or guidelines > Practice / clinical guidelines

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