Home > Risk of suicide following an alcohol-related emergency hospital admission: An electronic cohort study of 2.8 million people.

Bowden, Bethan and John, Ann and Trefan, Laszlo and Morgan, Jennifer and Farewell, Daniel and Fone, David [PLOS One] . (2018) Risk of suicide following an alcohol-related emergency hospital admission: An electronic cohort study of 2.8 million people. Public Library of Science. PLoS ONE, 13 (4) https://doi.org/10.1371/journal.pone.0194772

URL: http://journals.plos.org/plosone/article?id=10.137...

OBJECTIVE: Alcohol misuse is a well-known risk factor for suicide however, the relationship between alcohol-related hospital admission and subsequent risk of death from suicide is unknown. We aimed to determine the risk of death from suicide following emergency admission to hospital with an alcohol-related cause.

METHODS: We established an electronic cohort study of all 2,803,457 residents of Wales, UK, aged from 10 to under 100 years on 1 January 2006 with six years' follow-up. The outcome event was death from suicide defined as intentional self-harm (ICD-10 X60-84) or undetermined intent (Y10-34). The main exposure was an alcohol-related admission defined as a 'wholly attributable' ICD-10 alcohol code in the admission record. Admissions were coded for the presence or absence of co-existing psychiatric morbidity. The analysis was by Cox regression with adjustments for confounding variables within the dataset.

RESULTS: During the study follow-up period, there were 15,546,355 person years at risk with 28,425 alcohol-related emergency admissions and 1562 suicides. 125 suicides followed an admission (144.6 per 100,000 person years), of which 11 (9%) occurred within 4 weeks of discharge. The overall adjusted hazard ratio (HR) for suicide following admission was 26.8 (95% confidence interval (CI) 18.8 to 38.3), in men HR 9.83 (95% CI 7.91 to 12.2) and women HR 28.5 (95% CI 19.9 to 41.0). The risk of suicide remained substantial in subjects without known co-existing psychiatric morbidity: HR men 8.11 (95% CI 6.30 to 10.4) and women HR 24.0 (95% CI 15.5 to 37.3). The analysis was limited by the absence in datasets of potentially important confounding variables and the lack of information on alcohol-related harm and psychiatric morbidity in subjects not admitted to hospital.

CONCLUSION: Emergency alcohol-related hospital admission is associated with an increased risk of suicide. Identifying individuals in hospital provides an opportunity for psychosocial assessment and suicide prevention of a targeted at-risk group before their discharge to the community.


Item Type:Evidence resource
Drug Type:Alcohol
Intervention Type:AOD disorder, AOD disorder harm reduction
Source:PLOS One
Date:April 2018
Page Range:e0194772
Publisher:Public Library of Science
Volume:13
Number:4
EndNote:View
Subjects:B Substances > Alcohol
F Concepts in psychology > Specific attitude and behaviour > self-destructive behaviour > suicidal behaviour / suicide
J Health care, prevention and rehabilitation > Health related prevention > Health information and education > Suicide prevention
J Health care, prevention and rehabilitation > Care by type of problem > Emergency care
J Health care, prevention and rehabilitation > Health care programme or facility > Hospital
P Demography, epidemiology, and history > Population dynamics > Substance related mortality / death
VA Geographic area > Europe > United Kingdom > Wales

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