1  In This Issue [PDF]

4  Fetal Alcohol Spectrum Disorders: Research Challenges and Opportunities [PDF]
Kenneth R. Warren, Ph.D.; Brenda G. Hewitt; and Jennifer D. Thomas, Ph.D.

15  Maternal Risk Factors for Fetal Alcohol Spectrum Disorders: Not As Simple As It Might Seem [PDF]
Philip A. May, Ph.D., and J. Phillip Gossage, Ph.D.

27  Combination Drug Use and Risk for Fetal Harm [PDF]
Wei-Jung A. Chen, Ph.D., and Susan E. Maier, Ph.D.

29  Focus On: Epigenetics and Fetal Alcohol Spectrum Disorder [PDF]
Michael S. Kobor, Ph.D., and Joanne Weinberg, Ph.D.

38  Understanding the Effects of Prenatal Alcohol Exposure Using Three-Dimensional Facial Imaging [PDF]
Leah Wetherill, M.S., and Tatiana Foroud, Ph.D.

42  Discriminating the Effects of Prenatal Alcohol Exposure From Other Behavioral and Learning Disorders [PDF]
Claire D. Coles, Ph.D.

51  The Quest for a Neurobehavioral Profile of Heavy Prenatal Alcohol Exposure [PDF]
Sarah N. Mattson, Ph.D., and Edward P. Riley, Ph.D.

56  Focus On: Biomarkers of Fetal Alcohol Exposure and Fetal Alcohol Effects [PDF]
Ludmila N. Bakhireva, M.D., Ph.D., M.P.H., and Daniel D. Savage, Ph.D.

64  Behavioral Interventions for Children and Adolescents With Fetal Alcohol Spectrum Disorders [PDF]
Blair Paley, Ph.D., and Mary J. O’Connor, Ph.D.

76  Fetal Alcohol Spectrum Disorders: Experimental Treatments and Strategies for Intervention [PDF]
Nirelia M. Idrus, Ph.D., and Jennifer D. Thomas, Ph.D.

86  Prenatal Alcohol Exposure and Miscarriage, Stillbirth, Preterm Delivery, and Sudden Infant Death Syndrome [PDF]
Beth A. Bailey, Ph.D., and Robert J. Sokol, M.D.

92  Focus On: The Use of Animal Models for the Study of Fetal Alcohol Spectrum Disorders [PDF]
Shannon E. Wilson, D.V.M., Ph.D, and Timothy A. Cudd, D.V.M., Ph.D.

SPECIAL SECTION: Update on Brain Pathology

99  Focus On: Magnetic Resonance–Based Studies of Fetal Alcohol Spectrum Disorders in Animal Models [PDF]
Shonagh K. O’Leary-Moore, Ph.D.; Scott E. Parnell, Ph.D.; Elizabeth A. Godin, Ph.D.; and Kathleen K. Sulik, Ph.D.

106  Focus On: Neurotransmitter Systems [PDF]
C. Fernando Valenzuela, M.D., Ph.D.; Michael P. Puglia; and Stefano Zucca, M.Sc.

121  Focus On: Structural and Functional Brain Abnormalities in Fetal Alcohol Spectrum Disorders [PDF]
S. Christopher Nuñez, Ph.D.; Florence Roussotte; and Elizabeth R. Sowell, Ph.D.