Home > Buprenorphine-naloxone in the treatment of codeine dependence: a scoping review of clinical case presentations.

Van Hout, Marie Claire and Hearne, Evelyn and Bergin, Michael (2017) Buprenorphine-naloxone in the treatment of codeine dependence: a scoping review of clinical case presentations. International Journal of Mental Health and Addiction , 15 , (1) , pp. 224-237.


Misuse of prescribed and over the counter (OTC) codeine containing medicines is an increasing public health concern in recent times. Studies have called for low threshold treatment services for individuals experiencing codeine dependence using buprenorphine naloxone therapy. We present a scoping review of clinical case presentation literature on the use of buprenorphine-naloxone in the treatment of codeine dependence. Seven records (four single case studies and three case series) on codeine dependence treated with buprenorphine-naloxone were included. Five themes emerged following a review of the cases for the treatment of codeine dependence with buprenorphine-naloxone. They are: (1) Patient Profiles; (2) History of Codeine Misuse; (3) Medical Problems; (4) Use of Other Substances; and (5) Buprenorphine-naloxone in the treatment of Codeine Dependence. The review highlights the complexities of patients with regards to pain, psychiatric illness, poly substance use and iatrogenic dependence, with findings encouraging in terms of patient stabilisation and recovery.

Item Type:Article
Date:2017
Page Range:pp. 224-237
Publisher:Springer
Volume:15
Number:1
EndNote:View
Accession Number:HRB (Available)
Related URLs:
Subjects:A Substance use, abuse, and dependence > Prevalence > Problem substance use
B Substances > Opioids (opiates)
B Substances > Opioids (opiates) > Opioid product > Codeine
B Substances > Opioids (opiates) > Opioid product > Naloxone
B Substances > Opioids (opiates) > Opioid product > Buprenorphine / Suboxone
VA Geographic area > Europe > Ireland

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