Home > Dependence on Over the Counter (OTC) codeine containing analgesics: treatment and recovery with buprenorphine naloxone.

Van Hout, Marie Claire and Delargy, Ide and Ryan, Gerry and Flanagan, Siobhan and Gallagher, Hugh (2016) Dependence on Over the Counter (OTC) codeine containing analgesics: treatment and recovery with buprenorphine naloxone. International Journal of Mental Health and Addiction , 14 , (5) , pp. 873-883.


Misuse and dependence on prescribed and over the counter (OTC) codeine-combination analgesics is an emerging public health concern. We present a clinical case series of four adult patients dependent on OTC codeine combination analgesics in Ireland. Cases (two males/two females, aged 44–57 years) were consuming between 12 and 72 codeine-containing tablets/day. In three cases, consumption was linked to pain, with on-going misuse reflecting dependence on codeine. Cases were initiated on buprenorphine-naloxone (Suboxone®), stabilised on doses of between 4 mg/1 mg and 14 mg/3.5 mg per day and remain on treatment without additional opioid use, as verified by drug screening reports. Although anecdotal, these cases show the potential of effective opioid assisted treatment (OAT) using buprenorphine-naloxone (Suboxone®) to successfully treat this distinct form of opioid dependence disorder. Optimal service provision should recognise unique patient profiles and needs for this form of opioid dependence and incorporate psycho-social supports.

Item Type:Article
Date:2016
Page Range:pp. 873-883
Publisher:Springer
Volume:14
Number:5
EndNote:View
Accession Number:HRB (Available)
Related URLs:
Subjects:B Substances > Opioids (opiates)
B Substances > Opioids (opiates) > Opioid product > Codeine
B Substances > Opioids (opiates) > Opioid product > Naloxone
B Substances > Opioids (opiates) > Opioid product > Buprenorphine / Suboxone
J Health care, prevention and rehabilitation > Treatment and maintenance
VA Geographic area > Europe > Ireland

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