Home > Preventing opioid overdose deaths with take-home naloxone.

Strang, John and McDonald, Rebecca, eds. [EMCDDA] (2016) Preventing opioid overdose deaths with take-home naloxone. Luxembourg: Office for Official Publications of the European Communities. 104 p. EMCDDA Insights Series no. 20

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This publication examines the case for distributing naloxone, an emergency medication, to people who inject opioids such as heroin and to others who might witness an opioid overdose. Through its capacity to reverse opioid overdose, naloxone can save lives if administered in time. This comprehensive review looks at opioid overdose and how naloxone counteracts it, and discusses the circumstances of opioid overdose deaths and the use of naloxone in regular clinical practice. As well as documenting the historical development and spread of take-home naloxone programmes in Europe and beyond, the study looks at the practical side of their implementation, including the training of naloxone recipients in how to recognise and respond to an overdose. Although take-home naloxone is supported by the World Health Organization, the report finds that barriers to its access exist in Europe and considers how the availability of the intervention may be expanded.

Table of contents

  • Foreword
  • Executive summary
  • Acknowledgements
  • Introduction
  • Chapter 1: Pharmacology and physiological mechanisms of opioid overdose and reversal
  • Chapter 2: Emergency naloxone in regular clinical practice
  • Chapter 3: Opioid overdose deaths: risks and clusterings in time and context
  • Chapter 4: Historical summary of the development and spread of take-home naloxone provision
  • Chapter 5: Setting up take-home naloxone training and distribution programmes
  • Chapter 6: Options for the future: new products, new legislation, new initiatives
Item Type:Evidence resource
Publication Type:Report
Drug Type:Opioid
Intervention Type:AOD disorder harm reduction
Source:EMCDDA
Date:January 2016
Call No:REF, EMCDDA
Pages:104 p.
Publisher:Office for Official Publications of the European Communities
Corporate Creators:European Monitoring Centre for Drugs and Drug Addiction
Place of Publication:Luxembourg
EndNote:View
Accession Number:HRB 5282 (Available), HRB 5283 (Available)
Related URLs:
Subjects:B Substances > Opioids (opiates)
B Substances > Opioids (opiates) > Opioid product > Naloxone
G Health and disease > Substance use disorder > Drug use > Drug intoxication > Poisoning (overdose)
J Health care, prevention and rehabilitation > Substance use prevention > Substance use harm reduction
J Health care, prevention and rehabilitation > Basic prevention categories > Targeted prevention
VA Geographic area > Europe

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