Home > Possible association between passive smoking and lower exhaled nitric oxide in asthmatic children.

Warke, Timothy J and Mairs, Vivienne and Fitch, Patrick S and Ennis, Madeline and Shields, Michael D (2003) Possible association between passive smoking and lower exhaled nitric oxide in asthmatic children. Archives of Environmental Health , 58 , (10) , pp. 613-616.

In adults, both active and passive smoking reduce levels of exhaled nitric oxide (eNO); however, to date, passive exposure to environmental tobacco smoke (ETS) has not been shown to affect eNO in children. The authors recruited 174 asthmatic children (96 male, 78 female) and 79 nonasthmatic controls (46 male, 33 female) from a group of children aged 5 to 14 yr who attended a children's hospital for an outpatient visit or elective surgery. Each subject's exposure to ETS was ascertained by questionnaire, and their eNO levels were measured. Asthmatic children had higher eNO levels (ppb) than nonasthmatic children (p = 0.04), and asthmatic children exposed to ETS had significantly lower eNO levels than unexposed children (p = 0.005).

Exposure to ETS did not alter eNO levels in nonasthmatic children (p = 0.4). Results of the study suggest that ETS exposure is associated with lower eNO levels among childhood asthmatics. Consequently, ETS exposure may need to be considered when physicians interpret eNO levels in asthmatic children. Further study of the effects of ETS on eNO levels is recommended.


Item Type:Article
Date:2003
Page Range:pp. 613-616
Publisher:Taylor & Francis
Volume:58
Number:10
EndNote:View
Accession Number:HRB (Not in collection)
Related URLs:
Subjects:VA Geographic area > Europe > Northern Ireland
G Health and disease > State of health > Physical health
B Substances > Tobacco (cigarette smoking) > Secondhand smoke (passive smoking)
T Demographic characteristics > Child of substance user
B Substances > Tobacco (cigarette smoking) > Tobacco smoke (cigarette law / policy)
T Demographic characteristics > Child

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