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Home > Cannabis use and childhood trauma interact additively to increase the risk of psychotic symptoms in adolescence.

Harley, M and Kelleher, I and Clarke, Mary and Lynch, F and Arseneault, L and Connor, D and Fitzpatrick, C and Cannon, M (2010) Cannabis use and childhood trauma interact additively to increase the risk of psychotic symptoms in adolescence. Psychological Medicine , 40 , (10) , pp. 1627-1634.

URL: http://www.ncbi.nlm.nih.gov/pubmed/19995476

RESULTS: In separate analyses both cannabis use and childhood trauma were significantly associated with risk of experiencing psychotic symptoms. However, the presence of both childhood trauma and early cannabis use significantly increased the risk for psychotic symptoms beyond the risk posed by either risk factor alone, indicating that there was a greater than additive interaction between childhood trauma and cannabis use.

 

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