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Home > Opioid antagonists for alcohol dependence.

Rosner, Susanne and Hackl-Herrwerth, Andrea and Leucht, Stefan and Vecchi, Simona and Srisurapanont, Manit and Soyka, Michael [The Cochrane Library] . (2010) Opioid antagonists for alcohol dependence. John Wiley & Sons, Ltd. Cochrane Database of Systematic Reviews (12) DOI: 10.1002/14651858.CD001867.pub3


To determine the effectiveness and tolerability of opioid antagonists in the treatment of alcohol dependence.

Authors' conclusions:
Naltrexone appears to be an effective and safe strategy in alcoholism treatment. Even though the sizes of treatment effects might appear moderate in their magnitudes, these should be valued against the background of the relapsing nature of alcoholism and the limited therapeutic options currently available for its treatment.

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