This paper describes the efforts within the European Union to tackle the issue of social inclusion. Based on that, the text focuses on a particular aspect: the relationship between social inclusion and health regarding four main groups at risk for marginalisation: (undocumented) migrants, drug users, sex workers and youth at risk. Based on the experiences and results of the work of Correlation – European Network Social Inclusion & Health - the text describes approaches and methodologies to improve social inclusion and access to health for the target groups mentioned above