Disorders due to substance use include disorders that result from a single occasion or repeated use of substances that have psychoactive properties, including certain medications. Disorders related to fourteen classes or groups of psychoactive substances are included. Typically, initial use of these substances produces pleasant or appealing psychoactive effects that are rewarding and reinforcing with repeated use. With continued use, many of the included substances have the capacity to produce dependence. They also have the potential to cause numerous forms of harm, both to mental and physical health. Disorders due to harmful non-medical use of non-psychoactive substances are also included in this grouping.

Classified under this heading in ICD-11 are:

6C40 Disorders due to use of alcohol 

6C41 Disorders due to use of cannabis 

6C42 Disorders due to use of synthetic cannabinoids 

6C43 Disorders due to use of opioids 

6C44 Disorders due to use of sedatives, hypnotics or anxiolytics 

6C45 Disorders due to use of cocaine 

6C46 Disorders due to use of stimulants including amphetamines, methamphetamine or methcathinone 

6C47 Disorders due to use of synthetic cathinones 

6C48 Disorders due to use of caffeine 

6C49 Disorders due to use of hallucinogens 

6C4A Disorders due to use of nicotine 

6C4B Disorders due to use of volatile inhalants 

6C4C Disorders due to use of MDMA or related drugs, including MDA 

6C4D Disorders due to use of dissociative drugs including ketamine and phencyclidine [PCP] 

6C4E Disorders due to use of other specified psychoactive substances, including medications 

6C4F Disorders due to use of multiple specified psychoactive substances, including medications 

6C4G Disorders due to use of unknown or unspecified psychoactive substances 

6C4H Disorders due to use of non-psychoactive substances 

6A41 Catatonia induced by substances or medications 

6C4Y Other specified disorders due to substance use 

6C4Z Disorders due to substance use, unspecified 

Disorders due to addictive behaviours 

[For DSM notes see also, article from 2013, DSM-5 Criteria for substance use disorders: recommendations and rationale, and from the 2016 online book Impact of the DSM-IV to DSM-5 changes on the National Survey on Drug Use and Health]

See also, What is a substance use disorder? by the American Psyciatric Association