Home > Imaging features of soft-tissue infections and other complications in drug users after direct subcutaneous injection.

Johnston, C and Keogan, MT (2004) Imaging features of soft-tissue infections and other complications in drug users after direct subcutaneous injection. American Journal of Roentgenology , 182 , (5) , pp. 1195-1202.

URL: http://www.ajronline.org/cgi/content/full/182/5/11...

Drug abuse is a serious problem, both globally and at a local level, with more than 13,400 opiate abusers in Dublin, Ireland, alone. Infectious complications are responsible for 60-80 per cent of hospital admissions of IV drug users. In 2000, in the United Kingdom and Ireland, fatalities associated with soft-tissue inflammation and severe systemic sepsis were linked to 'skin popping' (injection of drugs into the skin and subcutaneous tissues rather than directly into a vein). Clostridium species were implicated in the pathogenesis. Superficial infection may progress to more widespread local or distant disease. Primary soft-tissue infections in IV drug users include cellulitis, abscess, myositis, pyomyositis, and necrotizing fasciitis. Secondary effects of IV drug use include septic arthritis and tenosynovitis, secondary osteomyelitis, vascular complications, soft-tissue ulceration, and fistula formation. In this review, the range of complications caused by skin popping that may develop will be shown. Early imaging to define disease extent and complications is important because clinical deterioration can be precipitous.


Item Type:Article
Date:2004
Call No:GG16, VH4.2
Page Range:pp. 1195-1202
Publisher:The American Roentgen Ray Society
Volume:182
Number:5
Keywords:Dublin, inflammation or infection, intracutaneous injection, opportunistic infection, secondary infection, subcutaneous injection
EndNote:View
Accession Number:HRB 2735 (Available)
Subjects:T Demographic characteristics > Intravenous / injecting drug user
G Health and disease > State of health > Physical health
G Health and disease > Disorder by cause > Communicable disease > Bacterial disease
A Substance use, abuse, and dependence > Effects and consequences

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