Home > Oral fluid collection by post for viral antibody testing.

O'Connell, T and Thornton, Lelia and O'Flanagan, D and Staines, A and Connell, J and Dooley, S and McCormack, G (2001) Oral fluid collection by post for viral antibody testing. International Journal of Epidemiology , 30 , pp. 298-301.

[img]
Preview
PDF (Oral fluid collection by post for viral antibody testing) - Accepted Version
64kB

URL: http://www.ije.oxfordjournals.org/cgi/reprint/30/2...

This study was undertaken to estimate the prevalence of hepatitis B virus exposure (HBV) in the population of Ireland, by using oral fluid (saliva) collection by post for hepatitis B anti-core antibody (anti-HBc). The sampling frame used was the Register for Electors for Irish parliamentary elections. A multistage stratified cluster sample was taken, and a total of 962 households were selected nationally. A four-letter approach was employed for sample collection. Households received an initial letter outlining the purpose of the study. This was followed by a letter containing six swabs for oral fluid collection, along with easy to follow instructions. Non-respondents received two reminder letters, and were also telephoned where possible. A telephone helpline was provided.

All testing was anonymous and unlinked. The study received a good response rate (60.4%), and more than 98% of the 1738 specimens were suitable for testing. The prevalence of anti-HBc in the Irish population was estimated to be .51%. The observed design effect was 1.29. From a literature review, this is the first study where a representative sample of a national population was asked to self-collect oral fluid samples and return these by post for serological testing. The technique may have future applications in epidemiological research.


Item Type:Article
Date:August 2001
Page Range:pp. 298-301
Publisher:Oxford University Press
Volume:30
Keywords:epidemiology, hepatitis antibodies, hepatitis B virus, human hepatitis B virus, Ireland, saliva analysis
EndNote:View
Related URLs:
Subjects:VA Geographic area > Europe > Ireland
P Demography, epidemiology, and history > Epidemiology
G Health and disease > Disorder by cause > Communicable disease > Hepatitis B
J Health care, prevention and rehabilitation > Health related prevention > Health information and education > Communicable disease control

Click here to request a copy of this literature (must be logged in)

Repository Staff Only: item control page