Home > Sensitive enzyme immunoassay for the detection of delta antigen and anti-delta,using serum as the delta antigen source.

Shattock, AG and Morgan, Bridget M (1984) Sensitive enzyme immunoassay for the detection of delta antigen and anti-delta,using serum as the delta antigen source. Journal of Medical Virology , 13 , (1) , pp. 73-82.

A sensitive enzyme-linked immunosorbent assay (ELISA, EIA) was developed for the detection of delta antigen in serum treated with Tween 20. The serum delta antigen so derived was used in an ELISA for anti-delta. Both tests were specific and more sensitive than radioimmunoassay (RIA) when applied to testing parenteral drug abusers. It is concluded that the different sources of delta-antigen used may account for the different sensitivities noted, and that delta antigenaemia in acute infection may be more frequently detectable than was first thought, amounting to 71% of those with delta infection in this study and that these sera are a convenient alternative source of antigen.

 

Item Type:Article
Date:1984
Call No:JG26
Page Range:pp. 73-82
Publisher:John Wiley
Volume:13
Number:1
EndNote:View
Accession Number:HRB 1538 (Available)
Subjects:G Health and disease > Disorder by cause > Communicable disease
J Health care, prevention and rehabilitation > Identification and screening
VA Geographic area > Europe > Ireland
G Health and disease > Disorder by cause > Communicable disease > Hepatitis B

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