Home > A meta-analysis of cognitive behavioral therapy for substance use disorder: treatment effects by comparator type and consumption and psychosocial outcomes.

Magill, Molly and Nichols, Lindsey M and Kiluk, Brian D and Alton, Emily and Tartak, Omeed and Ray, Lara A (2026) A meta-analysis of cognitive behavioral therapy for substance use disorder: treatment effects by comparator type and consumption and psychosocial outcomes. Behaviour Research and Therapy, 203, 105101. https://doi.org/10.1016/j.brat.2026.105101.

External website: https://www.sciencedirect.com/science/article/pii/...

OBJECTIVE: This meta-analysis examines cognitive-behavioral therapy (CBT) for substance use disorders (SUD). A comprehensive literature search was conducted through June of 2025. All available outcomes were extracted and grouped into thirteen categories (e.g., abstinence, quantity of use, cognitive changes, quality of life), and into two broader outcome classes (i.e., consumption; psychosocial). Robust variance estimation accounted for clustering of effect sizes at the study level.

Highlights
• This meta-analysis examines consumption and psychosocial functioning outcomes.
• Cognitive Behavioral Therapy (CBT) demonstrated efficacy overall.
• The most consistent effects were observed for consumption outcomes.
• Data supports adjunctive use of CBT for consumption and psychosocial outcomes.
• Residual heterogeneity suggests caution when interpreting effect size magnitude.


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