BACKGROUND: People experiencing homelessness (PEH) are disproportionately affected by frailty, yet few interventions have targeted this syndrome in this population.

AIM: To assess the feasibility, and potential impact of a combined exercise and nutritional intervention for PEH living with frailty.

DESIGN & SETTING: A single-arm feasibility trial in a GP clinic for PEH in Ireland.

METHOD: A two-month exercise and nutritional intervention tailored for PEH was offered to potential participants. Pre-frail and frail individuals attending a GP clinic for PEH in Ireland were invited to participate. The primary outcomes was feasibility, assessed using Bowen's framework. Secondary outcomes were based on potential impact and included frailty scores (Clinical Frailty Scale [CFS] and SHARE-Frailty Index [SHARE-FI]) and weight. A process evaluation explored participant experience.

RESULTS: Of 124 eligible individuals, 108 (87.1%) enrolled, and 75 (69.4%) completed follow-up. Among those followed up, 70 (93.3%) engaged with at least one component of the intervention, with the majority finding the intervention easy to follow. CFS and SHARE-FI scores improved following the intervention in those followed-up.

CONCLUSIONS: This study supports the feasibility of a primary care-based exercise and nutritional intervention for PEH living with frailty. The intervention appeared to be safe and to improve frailty status of participants and can inform the design of a definitive trial.