Silva, Stefani Gonzalez and Pedro, Maria Olivia Pozzolo and Castaldelli-Maia, Joao Mauricio (2026) Prevalence of alcohol use disorders in individuals with borderline personality disorder: a meta-analysis and meta-regression study. Sao Paulo Medical Journal, 144, (1), e2024480. https://doi.org/10.1590/1516-3180.2024.0480.R1.04112025.
External website: https://www.scielo.br/j/spmj/a/JnXxvS97zGdMzsKVyMr...
BACKGROUND: This review examined the prevalence rate of alcohol use disorders (AUDs)-including heavy episodic drinking, heavy drinking, alcohol abuse, and alcohol dependence-among individuals with borderline personality disorder (BPD).
OBJECTIVES: The primary objective of this meta-analysis and meta-regression study was to investigate the prevalence AUDs associated with BPD.
DESIGN AND SETTING: We searched PubMed, Google Scholar, Virtual Health Library (VHL/BVS), SciELO, LILACS, EMBASE, and PsycINFO for studies, reports, or abstracts published without language restrictions.
METHODS: We searched for reports published from database inception through March 2024. This study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and Meta-analysis Of Observational Studies in Epidemiology guidelines (MOOSE). Based on the extracted data, we performed meta-analyses and meta-regressions.
RESULTS: The final sample included 15 articles with 15,603 individuals aged 18 years or older with BPD. The prevalence of AUDs with BPD was 55.28%, while the prevalence of alcohol dependence (AD) was 44.59%, and alcohol abuse (AA) was 18.84%.
CONCLUSION: Our findings indicate a high prevalence of AUDs among individuals with BPD, underscoring the need for targeted prevention and treatment strategies. Integrated dual-diagnosis approaches addressing both disorders simultaneously are crucial for improving outcomes. This high prevalence has important implications for public health.
G Health and disease > State of health > Mental health
G Health and disease > Substance use disorder (addiction) > Alcohol use disorder
G Health and disease > Substance related disorder > Substance related mental health disorder > Dual diagnosis / comorbidity (mental health)
G Health and disease > Behavioural and mental health disorder (Psychosis / mood)
VA Geographic area > International
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