This EUDA Precursor Assessment Report examines the evidence on 2-bromo-3′-chloropropiophenone, evaluating its licit use in the EU and the extent of its use in illicit production.

2-Bromo-3′-chloropropiophenone is a chemical precursor used for the production of 3-CMC (3-cloromethcathinone or clophedrone) - a synthetic cathinone stimulant drug that has been present in the drug market in the European Union (EU) since at least 2014. The availability of 3-CMC in the EU appears to have increased significantly in 2022 and 2023, with more than 19 tonnes seized each year. This increasing availability seems to be driven mostly by large imports originating in India, but production within the EU has also been reported. 3-CMC has been under international control since December 2024.