This report presents HIV/AIDS surveillance data for 2024, which shows significant variation in epidemic patterns and trends across the World Health Organization (WHO) European Region. In 2024, 105 922 HIV diagnoses were reported in 49 of the 53 countries in the Region, including 24 164 from the countries of the European Union/European Economic Area (EU/EEA). This corresponds to a crude rate of 11.8 HIV diagnoses per 100 000 population overall, a slight (7.8%) decrease compared with the 2023 rate (12.8 per 100 000 population). However, 11 out of 49 countries still reported an increase in HIV diagnoses in 2024 compared to 2023.