Home > Substance use disorders: a call for a staging paradigm.

Bachi, Keren and Hurd, Yasmin L and Salsitz, Edwin A (2025) Substance use disorders: a call for a staging paradigm. Translational Psychiatry, 15, 261. https://doi.org/10.1038/s41398-025-03484-3.

External website: https://www.nature.com/articles/s41398-025-03484-3

Despite advances in the characterization of substance use disorders (SUDs) as chronic brain disorders, specific clinical stages have yet to be established similar to other chronic illnesses. A dynamic structured staging model for SUDs that incorporates multidimensional factors including social determinants of health, could improve personalized treatment and enhance clinical translation of addiction research.


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