This chapter reports results of studies that examined certain social issues associated with drug misuse, including housing, homelessness, public nuisance, and community problems. The need for more research into social and economic costs of drug misuse is highlighted. Findings from the first national survey of public attitudes to drugs, drug users, drug policy etc. carried by the Drug Misuse Research Division of the Health Research Board, are discussed. Some drug-related issues, which have been the subject of recent public debate, are outlined.