Home > The rise of novel, semi-synthetic 7-hydroxymitragnine products. [Letter]

Smith, Kirsten E and Boyer, Edward W and Grundmann, Oliver and McCurdy, Christopher R and Sharma, Abhisheak (2024) The rise of novel, semi-synthetic 7-hydroxymitragnine products. [Letter]. Addiction, Early online, https://doi.org/10.1111/add.16728.

External website: https://onlinelibrary.wiley.com/doi/10.1111/add.16...

Products containing the psychoactive botanical, Mitragyna speciosa, have transformed from simple leaf powders into an array of products, falling under the broad umbrella of ‘kratom’. Whole-leaf products contain consistent concentrations of kratom’s major alkaloid, mitragynine, and its metabolite 7-hydroxymitragynine; even among extracts, alkaloid concentrations often remain within self-adopted industry norms, with 7-hydroxymitragynine between 1 and 2% of the total content, or below the lower limit of quantification...


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